Chemical management and occupational cholangiocarcinoma among workers in printing industry
نویسندگان
چکیده
منابع مشابه
Cholangiocarcinoma among Workers in the Printing Industry: Using the Nordic Occupational Cancer Database to Elucidate a Cluster Report from Japan
inverse relation to blood lead level (SMRS 11.1, 3.2, 0.9. 0.8 by increasing category). Numbers were small for other causes of interest (stomach cancer n = 23, kidney cancer n = 28, brain cancer n = 31). SMRs for stroke were low (0.59, 0.57, 0.81. 0.87) but showed a borderline significant increasing trend in Poisson regression (p = -0.08). Conclusion We studied a large cohort with documented le...
متن کاملChemical exposure levels in printing workers with cholangiocarcinoma (second report).
OBJECTIVE In several Japanese printing plants, printing workers have suffered from cholangiocarcinoma. 1,2-dichloropropane (1,2-DCP) is considered to be a causative agent, and whether or not other chemicals also contribute to the development of this disease has not been conclusively determined. This study aimed to identify the chemicals used by seven printing workers who developed cholangiocarc...
متن کاملAcute and subacute symptoms among workers in the printing industry.
The study population comprised 52 male printers and 52 controls. Each person was interviewed about job history, general health, and work-related symptoms. Symptoms from eyes and airways, neurological symptoms, and general symptoms were recorded. A lung function test and a measurement of the sense of smell were also carried out. The printers had significantly more eye, airway, and neurological s...
متن کاملHypermutation and unique mutational signatures of occupational cholangiocarcinoma in printing workers exposed to haloalkanes
Cholangiocarcinoma is a relatively rare cancer, but its incidence is increasing worldwide. Although several risk factors have been suggested, the etiology and pathogenesis of the majority of cholangiocarcinomas remain unclear. Recently, a high incidence of early-onset cholangiocarcinoma was reported among the workers of a printing company in Osaka, Japan. These workers underwent high exposure t...
متن کاملTwo offset printing workers with cholangiocarcinoma.
OBJECTIVES Previously, the author reported a cluster of 11 cholangiocarcinoma cases exposed to 1,2-dichloropropane (1,2-DCP) and/or dichloromethane (DCM) in an offset proof-printing company. Before that report, the association between the two chemicals and cholangiocarcinoma had not been known. The current study describes two cholangiocarcinoma patients exposed to 1,2-DCP or DCM in different of...
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ژورنال
عنوان ژورنال: Sangyo Eiseigaku Zasshi
سال: 2016
ISSN: 1341-0725,1349-533X
DOI: 10.1539/sangyoeisei.wadai15005